Après ses altercations avec le Sénateur Perrin et la Dollhouse, Echo se retrouve seule au monde alors qu’elle essaye de lutter pour contrôler ses multiples personnalités. Topher découvre les dangers de la science qui provoquera des effets néfastes dans le futur, alors qu’Adelle s’engage dans une lutte de pouvoir sévère avec Harding.
After her entanglements with Senator Perrin and the DC Dollhouse, Echo finds herself out in the world-at-large as she struggles to control her multiple memory downloads, as well as those of her original memory of Caroline. Unsure who she is, Echo/Caroline calls upon the only person she can remember; Ballard, when she lands in a jam in a small town in Texas involving an illegal Mexican immigrant woman whom gets jailed by the local sheriff. Meanwhile, Topher discovers the dangers of science that will have devastating effects on the future over abusing the Active's imprints, while Adelle engages in a power struggle with Matthew Harding for control of the L.A. Dollhouse, and Boyd gets a phone call from someone in particular over Echo's whereabouts.